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Evidence

Scientific proof. How robust it is depends, among other things, on the type of study, the risk of bias and the body of studies as a whole. Missing evidence does not mean something is ineffective.

Also called
evidence-based, body of studies

“Evidence” means scientific proof. How robust it is depends, among other things, on the type of study, the risk of bias and the body of studies as a whole. In its recommendations, the 2021 S3 guideline distinguished “soll” (strong recommendation based on the evidence, grade A), “sollte” (grade B) and “kann” (open recommendation because of low evidence, grade 0). [1, Ch. C.1]

Important: if there is no evidence for a method, this does not mean it is ineffective, but that it has so far not been researched sufficiently. [1, Ch. C.1] The guideline expired on 23.03.2026. [2]

Sources and literature

  1. DGKJP/DGPPN et al.: Autismus-Spektrum-Störungen im Kindes-, Jugend- und Erwachsenenalter, Teil 2: Therapie. Interdisziplinäre S3-Leitlinie, AWMF-Reg.-Nr. 028-047, Langversion, Stand Text 02.05.2021. https://register.awmf.org/assets/guidelines/028-047l_S3_Autismus-Spektrum-Stoerungen-Kindes-Jugend-Erwachsenenalter-Therapie_2021-04_1.pdf
  2. DGKJP: Aktuelle Leitlinien (Übersicht mit AWMF-Registernummer und Gültigkeitsdatum). https://www.dgkjp.de/wissen/aktuelle-leitlinien/

In detail: How good is a study? Evidence and recommendations explained

Articles on this term

Related terms

  • Systematic review and meta-analysis

    A systematic review evaluates studies by set rules; a meta-analysis combines their results statistically. Definition with an example on prevalence.

  • S3 guideline

    S3 guideline: the highest development level of German medical guidelines. There are two on autism (diagnosis and therapy); both have now expired.

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